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Tumoral calcinosis in end stage renal disease

Department of Medicine, Tuen Mun Hospital, Hong Kong, China

Correspondence to:
Correspondence to:
Dr Tong;
khmtong@netvigator.com

Keywords: end stage renal disease; tumoral calcinosis

The first 150 words of the full text of this article appear below.

A 48 year old woman with end stage renal disease who had been on peritoneal dialysis since 1998 presented with multiple enlarging nodules over both hands (fig 1), especially around the wrists. They were non-tender and clinically resembled gouty tophi. The fasting serum urate concentration was normal, but serum parathyroid hormone and calcium-phosphate product were raised. On examination, two relatively large subcutaneous lesions were also found on her back. They were firm in consistency and slightly lobular in appearance, similar to those found on her hands. Radiography of the lesions revealed heavy calcification (figs 2 and 3). Fine needle aspiration of the hand nodules and her back lumps yielded thick milky white material, which under the microscope demonstrated some granular and crystalloid eosinophilic material with significant calcification and no viable cells. The clinical presentation and histological findings were characteristic of tumoral calcinosis.

View larger version (111K): [in this window] [in a new window]   Figure 1  Nodules on patient’s hands (published with . . . [Full text of this article]

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