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Deep jaundice in an adolescent

B Academic Department of Internal Medicine, Athens, Greece

Correspondence to:
Correspondence to:
Dr Deutsch;
kostam@ath.forthnet.gr

Submitted 11 November 2002
Accepted 24 January 2003

Keywords: Whipple’s disease; Tropheryma whippelii; jaundice; Epstein-Barr; cholestasis; haemolysis; infectious mononucleosis

The first 150 words of the full text of this article appear below.

A 16 year old girl, previously healthy, presented with a four day history of 39°C fever with chills, loss of appetite, and fatigue. During the past 24 hours, she had dark urine and became progressively jaundiced. She had never smoked or drunk alcohol and took no medications or illicit drugs. Her parents and sibling were in good health.

On examination she was alert but weak, with a presenting fever 39°C, blood pressure of 100/75 mm Hg, tachycardia (108 beats/min), and tachypnoea (26 breaths/min). The patient was obviously jaundiced and small, painless, tracheal lymph nodes were palpable. The liver was slightly enlarged and the spleen just palpable. There were no signs of chronic liver disease and a split lamp examination for Kayser-Fleischer rings gave negative results. Pregnancy was excluded.

Laboratory testing showed a haemoglobin concentration of 116 g/l (mean corpuscular volume 96.3 fl), leucocytes 13.6 x 10⁹/l with 34% . . . [Full text of this article]

Relevant Article

Deep jaundice in an adolescent
Postgrad. Med. J. 2003 79: 548-549. [Extract] [Full Text] [PDF]