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An unusual cause of peripheral neuropathy in a diabetic patient on dialysis: "a sural surprise"

Department of Renal Medicine, Guy’s Hospital, Guy’s, King’s and St Thomas’ Medical School, London

Correspondence to:
Correspondence to:
Dr David Goldsmith, Renal Unit, Guy’s Hospital, London SE1 9RT, UK;
david.goldsmith@gstt.sthames.nhs.uk

Submitted 23 September 2002
Accepted 3 December 2002

Keywords: prosthetic heart valves

The first 150 words of the full text of this article appear below.

Peripheral neuropathy is a common medical problem, with many potential aetiologies.¹ One of the commonest systemic diseases to cause a peripheral neuropathy is diabetes mellitus.^2,3 Patients with end stage renal failure are also prone to develop peripheral neuropathy, in part related to how well uraemic toxins are removed by renal replacement therapy.⁴

We present the case of a woman with diabetes, on dialysis treatment, who developed an acute severe peripheral neuropathy. There were unusual clinical and investigational findings that mandated further diagnostic work-up.

CASE REPORT
An overweight woman, born in Antigua in 1948, developed type II diabetes mellitus in 1979. From 1983 she required oral hypoglycaemic agents then insulin. In 1994 she developed heavy proteinuria and impaired renal function (inulin glomerular filtration rate 52 ml/min corrected for body surface area, n=125 ml/min/1.73 m²) and required retinal laser photocoagulation.

She was lost to follow up, but reappeared in 1998 no longer . . . [Full text of this article]

Relevant Article

An unusual cause of peripheral neuropathy in a diabetic patient on dialysis: "a sural surprise"
Postgrad. Med. J. 2003 79: 480-481. [Extract] [Full Text] [PDF]