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Gene therapy in head and neck cancer: a review

¹ Molecular Oncology, Cancer Research UK, Barts and The London NHS Trust, London, UK
² Department ENT, Barts and The London NHS Trust, London, UK
³ Department of Clinical Oncology, Charing Cross Hospital, Hammersmith, London, UK

Correspondence to:
Dr E Chisholm, 44 Eastbury Grove, London W4 2JY, UK; edwardchisholm{at}doctors.org.uk

ABSTRACT
Gene therapy for cancer is a rapidly evolving field with head and neck squamous cell cancer being one of the more frequently targeted cancer types. The number of clinical trials in the UK is growing and there is already a commercially available agent in China. Various gene therapy strategies along with delivery mechanisms for targeting head and neck cancer are reviewed.

Keywords: head and neck; squamous cell; cancer; gene therapy; gene