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Postgraduate Medical Journal 2005;81:83-86
© 2005 Fellowship of Postgraduate Medicine

REVIEW

Urinary tract infections: new insights into a common problem

R Kucheria 1, P Dasgupta 1, S H Sacks 2, M S Khan 1, N S Sheerin 2

1 Department of Urology, Guy’s and St Thomas’ Hospital NHS Trust, London, UK
2 Department of Renal Medicine and Transplantation, King’s College London, Guy’s Hospital

Correspondence to:
Correspondence to:
MrR Kucheria
Department of Urology, 1st Floor Thomas Guy House, Guy’s Hospital, London SE1 9RT, UK; rkucheria{at}hotmail.com

This review discusses recent advances in the understanding of how the common pathogen, uropathogenic Escherichia coli, interacts with the host to lead to infection.

Abbreviations: UTI, urinary tract infection; UPEC, uropathogenic Escherichia coli; LPS, lipopolysaccharide; CNF, cytotoxic necrotising factor; THP, Tamm-Horsfall protein; TLR, toll-like receptor; MAC, membrane attack complex

Keywords: vaccine; urinary tract infections




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