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Unoperated tetralogy of Fallot: case report of a natural survivor who died in his 73rd year; is it ever too late to operate?

¹ Department of Internal Medicine, Duke University Medical Centre, Durham, North Carolina, USA
² GUCH Unit, Department of Cardiology, Norfolk and Norwich University NHS Hospital, Norwich, UK
³ Department of Renal Medicine, Norfolk and Norwich University NHS Hospital

Correspondence to:
Correspondence to:
Dr L J Freeman
GUCH Unit, Department of Cardiology, Norfolk and Norwich University NHS Hospital, Colney Lane, Norwich NR4 7UZ, UK; leisa.freeman{at}nnuh.nhs.uk

The case history is described of a man in his 73rd year who was one of the oldest surviving patients with uncorrected tetralogy of Fallot (ToF) before succumbing with renal failure. Factors contributing to his longevity included small pulmonary arteries and presumed slow development of subpulmonary obstruction together with moderate concentric left ventricular hypertrophy—features previously seen in long term survivors. Less than 3% of all patients with uncorrected ToF survive beyond their 40s but late operative repair is still a valuable option. Practicalities of renal dialysis in the presence of an intracardiac shunt are considered.

Abbreviations: ToF, tetralogy of Fallot; RVH, right ventricular hypertrophy; LA, left atrium; RA, right atrium; LV, left ventricle; RVOT, right ventricle outflow tract; VSD, ventricular septal defect; LAD, left anterior descending

Keywords: tetralogy of Fallot