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Postgraduate Medical Journal 2003;79:535-538
© 2003 Fellowship of Postgraduate Medicine


CASE REPORT

Sarcoidosis and HIV infection: a case report and a review of the literature

M Trevenzoli 1, A M Cattelan 1, F Marino 2, U Marchioro 3, P Cadrobbi 1

1 Division of Infectious Diseases, General Hospital and University of Padua, Italy
2 Department of Pathology
3 Radiologic Unit

Correspondence to:
Correspondence to:
Dr Anna Maria Cattelan, Division of Infectious Diseases, General Hospital and University of Padova, Via Giustiniani 2, 35128 Padova, Italy;
aacattelan{at}hotmail.com


ABSTRACT
Sarcoidosis occurring in patients with AIDS is rare. This infrequent association has been attributed to the impairment of the immune system that may interfere with the granuloma formation in HIV infected patients. However, the introduction of highly active antiretroviral therapy (HAART) has brought about a substantial and sustained increase in CD4+ T lymphocyte cells, and has consequently led to the development of the so called "immune restoration disease".

The case of an HIV infected man who developed sarcoidosis after the initiation of HAART is described. Skin nodule images and histological specimens are reported. The association between sarcoidosis and HIV infection is also reviewed.


Keywords: sarcoidosis; HIV infection; HAART

Abbreviations: BAL, broncheoalveolar lavage; HAART, highly active antiretroviral therapy; SACE, serum angiotensin converting enzyme




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F G Joseph and N J Scolding
Sarcoidosis of the nervous system
Practical Neurology, August 1, 2007; 7(4): 234 - 244.
[Abstract] [Full Text] [PDF]




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