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Malignant potential in a Brunner’s gland hamartoma

¹ Department of Gastroenterology, City General Hospital, Stoke-on-Trent
² Department of Gastroenterology, Manor Hospital, Walsall
³ Department of Histopathology, Manor Hospital, Walsall

Correspondence to:
Correspondence to:
Dr Brookes;
mbro453398{at}aol.com

ABSTRACT
Brunner’s gland hamartomas are rare tumours of the duodenum. These lesions have previously been described as being benign, with no malignant potential. A case report is presented of a Brunner’s gland hamartoma, whose histology revealed a focus of well marked epithelial dysplasia. This case suggests a dysplastic stage in the natural history of Brunner’s gland hamartoma, and questions the malignant potential of these lesions.

Keywords: adenoma; Brunner’s gland hamartoma; dysplasia