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Recurrent aseptic meningitis due to different non-steroidal anti-inflammatory drugs including rofecoxib

Department of Internal Medicine, Mercer University School of Medicine, Macon, Georgia

Correspondence to:
Correspondence to:
Dr Ashwath;
Mahi_Lakshmi{at}yahoo.com

ABSTRACT
Aseptic meningitis can be caused by viruses, drugs, and connective tissue disorders. The most common drugs causing it include antibiotics like trimethoprim-sulfamethoxazole, non-steroidal anti-inflammatory drugs (NSAIDs), intravenous immunoglobulins, intrathecal agents, vaccines, and monoclonal antibodies. A patient who had aseptic meningitis from three different NSAIDs including rofecoxib is presented.

Keywords: non-steroidal anti-inflammatory drugs; adverse drug reaction; rofecoxib

Abbreviations: COX, cyclo-oxygenase; DIAM, drug induced aseptic meningitis; NSAIDs, non-steroidal anti-inflammatory drugs

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				H. T. Nguyen and D. N Juurlink Recurrent Ibuprofen-Induced Aseptic Meningitis Ann. Pharmacother., March 1, 2004; 38(3): 408 - 410. [Abstract] [Full Text] [PDF]