Postgraduate Medical Journal, 1983, Vol 59, 514-515
Transient, selective factor X deficiency and acute liver failure following chest infection treated with erythromycin BP
JP Hosker and DP Jewell
A 57-year-old man developed symptoms of a respiratory tract infection which
was treated with erythromycin BP. He subsequently went into acute liver
failure. Investigation of a very prolonged prothrombin time revealed a
marked, selective factor X deficiency (1% of normal activity). He later
recovered virtually normal liver function and completely normal factor X
activity.